What are the advantages of PGD?
The ultimate advantage of PGD is the increased likelihood of a healthy baby.
Greater live birth rate
35 year old: |
40 year old: |
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Lower risk of malformed babies and pregnancy termination
The chance of a woman delivering a baby with a genetic disorder is 1% if she is 35-39 years old and 3% if she is 40-45. PGD decreases the chances of having to terminate a pregnancy if a foetus is found to be abnormal. So far, from the data available from 143 conceptions achieved through PGD, two (1.4%) were chromosomally abnormal compared with 2.7% expected for that group of patients according to their maternal ages.
Reduction in spontaneous miscarriage
In women 35 or older about 15% of pregnancies spontaneously abort, with 50% or more of those miscarriages being caused by abnormalities. By transferring only normal embryos the number of pregnancies reaching term should increase. In one study a significant reduction in spontaneous miscarriages occurred after PGD, from 23% to 9%. The increase in implantation and the significant decrease in spontaneous miscarriages resulted in a significant increase in ongoing pregnancies and delivered babies.
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